Our Mission

Bringing hope to late-stage cancer patients who are running out of therapeutic options and time

About Travera

Travera assists oncologists in selecting treatments for their patients with our revolutionary cancer therapy guidance test that predicts which cancer drugs are most likely to be effective for each cancer patient.

Using a disruptive single-cell measurement technology invented at MIT that measures the ex vivo growth response of live tumor cells to candidate drugs, Travera has overcome the problems that have prevented the many previous generations of therapy guidance tests from being effective in clinical practice.

Travera’s 2-day Rapid Therapy Guidance™ test enables patients who are running out of therapeutic options to discover additional options and continue their battle against cancer.

Our Commitment

When patients feel out of options, they lose the strength and will to continue the battle against their cancer. Travera is committed to improving both patient experience and outcomes.

We offer physicians an effective way to personalize their patients’ cancer treatment and potentially increase their therapeutic options in an unprecedented two-day turnaround.

From Innovation to Implementation

The Suspended Microchannel Resonator (SMR), invented in the Manalis lab at MIT, was developed to measure the weight of individual cells. We formed Travera to use this breakthrough technology to measure the growth response of live cancer cells. Since 2018, we have been conducting clinical studies at prominent academic medical institutions in the United States, gathering clinical evidence for the accuracy of our rapid therapy guidance testing process. Our early results are promising, achieving 80% predictive accuracy. 

Our CLIA-certified Laboratory Developed Tests (LDTs) currently span virtually all cancers (breast, lung, colorectal, multiple myeloma, AML, etc.). Upon completion of ongoing clinical validation studies, our tests will span virtually all cancer drugs (immunotherapies, targeted inhibitors, cytotoxics, etc.). 

A world-Class team

 

Each member of our team of business, research, and clinical experts has been trained in the world’s top institutions. Travera’s team is highly experienced and is dedicated to supporting the treatment and well-being of patients diagnosed with late-stage, relapsed, or rare cancers.

 

Leadership Team

  • Mark Stevens is the interim CEO and co-founder of Travera. He joined Travera as VP, Clinical Development from Dana Farber Cancer Institute, where, as a research scientist, he led a team working on the development of the MAR biomarker platform across malignancies.

    Previously, Mark established more than a decade of successful, biology-focused interdisciplinary pursuits.

    He received his B.S. in Biochemistry from the University of Washington, where his research focused on the biophysical properties of cell membranes. After a brief stint at the imaging cytometer start-up Amnis, he started his Ph.D. in Biology at MIT. His thesis work at MIT’s Koch Institute for Integrative Cancer Research focused on translational and biological applications of single-cell biophysical measurements, spanning single-cell cancer metabolism to cancer biomarker development.

  • Rob Kimmerling is the Chief Technology Officer and a co-founder of Travera. He received his B.E. in Biomedical Engineering from Stony Brook University, where he first started working on microfluidic device development for single-cell analysis applications.

    Rob continued in this field at MIT where he earned his Ph.D. in Biological Engineering. His graduate work focused on developing novel microfluidic platforms for collecting linked measurements of single-cell biophysical and transcriptional properties.

    After graduating, he continued developing these projects as a Research Scientist at the Koch Institute for Integrative Cancer Research at MIT, where he led a team utilizing these approaches to characterize transcriptional signatures associated with single-cell drug susceptibility in various malignancies.

  • Selim Olcum is the VP of Engineering and a co-founder of Travera.

    Prior to this, he was a research scientist at the Koch Institute for Integrative Cancer Research at MIT. During his tenure at MIT, he invented several techniques enabling the rapid assessment of single-cell growth.

    Dr. Olcum received his post-doctoral training at the Department of Biological Engineering at MIT. During this time, he developed high-precision, real-time measurement methods for the attogram-level analysis of cell-derived vesicles and nanoparticles in suspension.

    He received his B.S., M.S., and Ph.D. degrees all in Electrical Engineering from Bilkent University, Turkey. His dissertation work focused on MEMS-based ultrasound transducers for biomedical applications. He has co-authored over 40 journal papers and conference proceedings and is the inventor of several patents.

  • Dennis Watson joined Travera in July of 2022 as the Vice President of Business Development. He brings 15 years of extensive sales and management experience in the oncology molecular diagnostic space.

    Dennis spent nearly 10 years with Agendia, beginning as a field-based sales professional, working his way up to gain experience in multiple facets of the business, receiving top-tier awards and recognition throughout his tenure. He served 4 years as a Regional Director in the Central US, before moving on to lead the US commercial sales organization in January of 2018. During his 4-year tenure as the VP of US Sales over the US and PR, he led Agendia to record-breaking years of growth and expansion resulting from a shifted strategic focus and relaunch of key product lines through enhanced product positioning.

    Prior to his work with Agendia, Dennis spent 5 years with the Breast Oncology division of Myriad Genetics. Before Myriad Genetics, he also held positions in the pharmaceutical, industrial services, and web services industries.

    Dennis has a Bachelor of Science degree from Ball State University, where he graduated with honors and was a National Honor Society member.

  • Scott Manalis is a co-founder of Travera and the David H. Koch (1962) Professor in Engineering at MIT with faculty appointments in the biological and mechanical engineering departments.

    Scott is the associate department head of the biological engineering department and a member of the Koch Institute for Integrative Cancer Research and MIT’s Center for Precision Cancer Research. His research group develops novel instrumentation for cancer research.

    Dr. Manalis was the recipient of the Presidential Early Career Award for Scientists and Engineers (PECASE) from the Department of Defense. He was previously selected by Technology Review magazine as one of the 100 innovators under the age of 35 whose work and ideas "will have a deep impact on how we live, work and think in the century to come."

    He received a B.S. degree in physics from the University of California, Santa Barbara, and a Ph.D. degree in applied physics from Stanford University.

  • Before co-founding Travera and joining the Travera Board of Directors in 2018, David Margulies, M.D. founded, co-founded, and participated as a Director and Senior Executive of a number of companies in the clinical computing, molecular diagnostics, and biotechnology fields.

    In the early 1980s, he co-founded and led BRS Medical, later acquired by WB Saunders and Elsevier North Holland. In the mid-1980s, while CIO at Boston Children’s Hospital, he led the design of software acquired by Cerner to be the basis of Cerner’s EMR.

    He became EVP, Chief Scientist, and a BOD member at Cerner in 1990. In 1996, he co-founded and was a Director of CareInsite, later acquired by WebMD in 2000. In 2000, he became co-founder, CEO, and Chairman of Correlagen Diagnostics, which was acquired by LabCorp in 2011 to be its genomic center of excellence.

    Dr. Margulies returned to Boston Children’s Hospital in 2011 as VP of Strategy and led the development of the institution’s genomic medicine strategy. In 2013, he co-founded and was Chairman of Q-State Biosciences, a Cambridge-based biotechnology company.

    Over the years, Dr. Margulies has served on numerous other public and private boards, including D2 Hawkeye (acquired by Verisk), ObMedical (acquired by Philips), Circulation (acquired by Logisticare), Generation Health (acquired by CVS), Claritas Genomics (acquired by Q-State Biosciences), Variantyx, and Commonwealth Care Alliance.

    Dr. Margulies received his B.A. from Amherst College and his M.D. from Harvard Medical School. He completed his clinical training and board certification in Internal Medicine at Columbia College of Physicians and Surgeons. Dr. Margulies recently retired from the faculties of Genetics and Bioinformatics at the Harvard Medical School.

 

Advisory Team

  • Dr. Keith Ligon is a Physician-Scientist with expertise in neuropathology and oncology-focused on improving the diagnosis and treatment of cancer.

    He attended medical school and received his Ph.D. at the University of Texas-Houston Medical School and his M.D. Anderson Cancer Center.

    Currently, he is an Associate Professor of Pathology at Harvard Medical School with joint appointments at the Dana-Farber Cancer Institute, the Broad Institute, and Brigham and Women’s Hospital (BWH).

    He is the Chief of Neuropathology at BWH/DFCI and the Director of the Center for Patient-Derived Models (CPDM) at DFCI. His research and clinical activities have improved the scientific understanding of brain tumors. He has also led efforts to train neuropathologists in the utilization of genomic tests in practice and led genomically informed clinical trials development at the local and national consortium levels.

  • David Weinstock is the Vice President of Discovery Oncology at Merck. He was previously a Professor of Medicine and Pediatrics at Harvard Medical School and an Independent Investigator at the Dana-Farber Cancer Institute. Dr. Weinstock has published over 200 articles and book chapters focused on the biology of cancer or treatment of patients with cancer. He was a National Cancer Institute Outstanding Investigator and a Paul G. Allen Institute Investigator. He now leads the global effort to develop new cancer therapeutics through preclinical development for Merck.

  • Steve Wasserman is a senior lecturer in the Biological Engineering Department at MIT, where he teaches hands-on lab courses in the area of bioinstrumentation (20.309 and 20.345) that demand building, debugging, iteration, and understanding of complex systems and processes. His classes teach how to create mental models of complex systems and apply those models to achieve breakthrough performance.

    Steve is the Consulting Director of Engineering at Q-State Biosciences, and he also develops instruments for academic and industrial labs.

    Previously, Steve developed high-tech products in the Silicon Valley, working at Apple, Microsoft, WebTV, and 3DO. His interests and skills include optics, electronics, woodworking, glass blowing, and computer programming.

  • Clifford Reid is the former founding CEO of Travera. Before joining Travera, Dr. Reid was the founding Chairman, President, and Chief Executive Officer of Complete Genomics (NASDAQ: GNOM), a leading developer of whole human genome DNA sequencing technologies and services.

    Prior to Complete Genomics, he founded two enterprise software companies: Eloquent (NASDAQ: ELOQ), an internet video company, and Verity (NASDAQ: VRTY), an enterprise search engine company.

    Dr. Reid is on the Visiting Committee of the Biological Engineering Department at the Massachusetts Institute of Technology (MIT), a member of the MIT Corporation Development Committee, and an advisor to Warburg Pincus.

    He earned an S.B. in Physics from MIT, an MBA from the Harvard Business School, and a Ph.D. in Management Science and Engineering from Stanford University.

Investors

 

Travera’s Laboratory

Travera’s CLIA-certified lab is located in Medford, Massachusetts, just four miles from MIT, where we maintain close ties with our cancer research partners.

Lab address: 200 Boston Ave., Suite 1500 Medford, MA 02155.

CLIA number: #22D2229321

 

Contact Us

Our goal is to bring you hope and an improved outcome.
Please reach out to us anytime and we will respond within 24 hours.